Search on: SUPRANUCLEAR PALSY, PROGRESSIVE 
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Descriptor English:   Supranuclear Palsy, Progressive 
Descriptor Spanish:   Parálisis Supranuclear Progresiva 
Descriptor Portuguese:   Paralisia Supranuclear Progressiva 
Synonyms English:   Steele-Richardson-Olszewski Syndrome
Ophthalmoplegia, Progressive Supranuclear
Progressive Supranuclear Ophthalmoplegia  
Tree Number:   C10.228.140.079.882
C10.228.662.700
C10.292.562.750.500
C10.574.945.500
C10.597.622.447.690
C11.590.472.500
C23.888.592.636.447.690
Definition English:   A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7) 
History Note English:   1987 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DH diet therapy
DT drug therapy EC economics
EM embryology EN enzymology
EP epidemiology EH ethnology
ET etiology GE genetics
HI history IM immunology
ME metabolism MI microbiology
MO mortality NU nursing
PS parasitology PA pathology
PP physiopathology PC prevention & control
PX psychology RA radiography
RI radionuclide imaging RT radiotherapy
RH rehabilitation SU surgery
TH therapy US ultrasonography
UR urine VE veterinary
VI virology  
Record Number:   19356 
Unique Identifier:   D013494 

Occurrence in VHL:
 

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